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Pediatric Neurogastroenterology and Motility Disorders: What Role Does Endoscopy Play?

Julie Khlevner1, Dhiren Patel2, Leonel Rodriguez3

  • 1Division of Pediatric Gastroenterology, Hepatology and Nutrition, Columbia University Vagelos College of Physicians and Surgeons, Gastrointestinal Motility Center, NewYork Presbyterian Morgan Stanley Children's Hospital, 622 West 168th Street, PH 17, New York, NY 11032, USA.

Gastrointestinal Endoscopy Clinics of North America
|March 22, 2023
PubMed

Insights

Pediatric neurogastroenterology and motility disorders are increasingly managed with advanced endoscopic techniques. These innovations are transforming the diagnosis and treatment of complex gastrointestinal conditions in children.

Area of Science:

  • Pediatric Gastroenterology
  • Motility Disorders
  • Gastrointestinal Endoscopy

Background:

  • Pediatric neurogastroenterology and motility (PNGM) disorders are common, severe, and difficult to diagnose/treat.
  • Recent advancements have significantly improved the management of these conditions.

Purpose of the Study:

  • To review the emerging role of diagnostic and therapeutic endoscopy in PNGM disorders.
  • To highlight novel endoscopic modalities and their impact on patient care.

Main Methods:

  • Review of recent literature on endoscopic advancements in pediatric gastroenterology.
  • Focus on functional lumen imaging probe, per-oral endoscopic myotomy (POEM), gastric-POEM, and electrocautery incisional therapy.

Main Results:

  • Diagnostic and therapeutic endoscopy are now valuable tools for PNGM disorders.
  • Novel endoscopic techniques have reshaped the diagnostic and therapeutic approaches.
  • Endoscopy is applicable across various gastrointestinal segments and gut-brain axis disorders.

Conclusions:

  • Therapeutic and diagnostic endoscopy represent a significant advancement in managing pediatric GI motility disorders.
  • These endoscopic innovations offer new hope for children with complex gastrointestinal conditions.

Keywords:
Colonic manometryFunctional lumen imaging probe (FLIP)GI motilityGastrointestinal endoscopyNeurogastroenterology and motilityPediatricsPeroral endoscopic myotomy (POEM)Volvulus

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