Related Experiment Video
Updated: Aug 6, 2025
06:37
Staphylococcus aureus Growth using Human Hemoglobin as an Iron Source
Published on: February 7, 2013
16.8K
Hemoglobin Louisville: A Case Report
Ionela Morosanu1, Yaniv Ergas2, Martina Cade3
1is staff CRNA University of Maryland Medical Center Baltimore, Maryland.
AANA Journal
|March 23, 2023
Summary
This case study highlights anesthetic management for a patient with Hemoglobin Louisville, a rare genetic condition. Understanding hemoglobinopathies is crucial for perioperative care, especially with low baseline oxygen saturation.
Area of Science:
- Anesthesiology
- Hematology
- Genetics
Background:
- Case study of a patient with Hemoglobin Louisville, a rare hemoglobinopathy.
- Patient presented with baseline low oxygen saturation (SpO2) in the 80s.
- Focus on anesthetic management during an elective procedure.
Observation:
- Noninvasive pulse oximetry revealed persistently low SpO2.
- The patient's medical history included Hemoglobin Louisville.
- Anesthesia details and physiological review are presented.
Findings:
- Discussion of the physiological implications of Hemoglobin Louisville.
- Analysis of the anesthetic approach for this specific genetic mutation.
- Low SpO2 in patients with rare hemoglobin variants requires careful consideration.
Implications:
- Highlights the importance of understanding rare hemoglobinopathies for anesthesia providers.
- Emphasizes the need for tailored perioperative care strategies.
- Informs the anesthesia community on managing patients with unexpected hypoxemia due to genetic factors.
Keywords:
Hemoglobin BucurestiHemoglobin Louisvillehemoglobin-oxygen affinityhemoglobinopathieshypoxiaMore Related Videos
Related Concept Videos
01:57Gene Families
8.9K
Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
8.9K
01:24Hemoglobin
3.9K
Hemoglobin is a globular protein made up of four subunits. Two of these subunits are alpha chains, and the other two are beta chains. Each subunit contains a molecule of heme, which has an iron atom and can bind to oxygen. When an oxygen molecule binds to one heme group, it changes the shape of hemoglobin, making it easier for the other heme groups to bind oxygen as well.
When all four heme groups are bound to oxygen, the resulting molecule is called oxyhemoglobin. As a result, arterial blood...
When all four heme groups are bound to oxygen, the resulting molecule is called oxyhemoglobin. As a result, arterial blood...
3.9K
02:15Protein and Protein Structure
79.9K
Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme...
A protein's shape is critical to its function. For example, an enzyme...
79.9K
02:45Blood Transfusion and Agglutination
11.0K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
11.0K
01:15Blood Transfusion
636
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
636
02:20Blood Types
17.9K
Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
17.9K