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Intracellular generation of electronically excited states. Polymorphonuclear leukocytes challenged with a precursor
Biochimica Et Biophysica Acta
|May 2, 1986
Abstract:
When the enol of isobutanal is added to polymorphonuclear cells, it undergoes an intracellular, myeloperoxidase-catalyzed aerobic oxidation with the formation of triplet acetone. The latter induces considerable damage if the enol concentration exceeds 2 mM. Cells which do not have myeloperoxidase are not damaged.