Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Underground vs outdoor air in the "Wieliczka" Salt Mine health resort: particulate matter and selected gaseous pollutants.

Environmental geochemistry and health·2026
Same author

Analysis of the Degradation Pathways, Cytotoxicity, and Antimicrobial Properties of Block Amphiphilic Aliphatic Polyesters Containing Amine and Hydroxyl Groups.

Chemistry, an Asian journal·2026
Same author

Antithrombotic Polymers: A Narrative Review on Current and Future Strategies for Their Design, Synthesis, and Application.

International journal of molecular sciences·2026
Same author

Special Issue: Polymers, Polymer Blends, and Polymeric Drug Release Systems with Antiviral or Antibacterial Effect-2nd Edition.

International journal of molecular sciences·2025
Same author

Assessing Label Stability in Oligopeptide-Modified Polymer Filament for Advanced Materials: Ultraviolet Exposure and Biodegradation Study.

ACS sustainable chemistry & engineering·2025
Same author

Evaluation of Ultrasonic Spray Method for Application of Sirolimus-Eluting Coating on Bioresorbable Vascular Scaffolds.

International journal of molecular sciences·2025

Related Experiment Video

Updated: Aug 5, 2025

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

19.2K

Biodegradable Block Poly(ester amine)s with Pendant Hydroxyl Groups for Biomedical Applications.

Natalia Śmigiel-Gac1, Anna Smola-Dmochowska1, Henryk Janeczek1

  • 1Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 41-819 Zabrze, Poland.

Polymers
|March 29, 2023
PubMed
Summary

Researchers synthesized novel amphiphilic block terpolymers with biodegradable polyesteramine blocks. These materials exhibit tunable properties, including antibacterial activity and water wettability, for advanced applications.

Keywords:
aliphatic polyesterantibacterial polymerbiodegradable polymerfunctional polymerwettability

More Related Videos

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
10:53

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Published on: October 10, 2016

14.1K
Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery
08:09

Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery

Published on: August 6, 2019

5.8K

Related Experiment Videos

Last Updated: Aug 5, 2025

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

19.2K
Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
10:53

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Published on: October 10, 2016

14.1K
Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery
08:09

Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery

Published on: August 6, 2019

5.8K

Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Biomaterials Engineering

Background:

  • Biodegradable and biocompatible polymers are crucial for advanced medical and material applications.
  • Amphiphilic block copolymers offer unique properties due to their distinct hydrophilic and hydrophobic segments.
  • Polyesteramines present an opportunity to incorporate both biodegradability and reactive amine functionalities.

Purpose of the Study:

  • To synthesize and characterize novel amphiphilic block terpolymers.
  • To create biodegradable materials with tunable hydroxyl/amino group content.
  • To investigate the antibacterial properties and surface wettability of the synthesized terpolymers.

Main Methods:

  • Copolymerization of L-lactide and glycolide using macroinitiators with protected functional groups.
  • Deprotection of hydroxyl and amine groups to yield functional terpolymers.
  • Characterization using proton nuclear magnetic resonance (¹H NMR), Fourier-transform infrared spectroscopy (FTIR), gel permeation chromatography (GPC), and differential scanning calorimetry (DSC).

Main Results:

  • Successfully synthesized amphiphilic block terpolymers with molecular masses ranging from 5,000 to 15,000 g/mol.
  • Achieved tunable surface wettability (contact angle 50°–20°) based on hydrophilic block composition.
  • Demonstrated high crystallinity in terpolymers with amino groups, with melting points between 90 °C and 170 °C.

Conclusions:

  • The synthesized terpolymers are biodegradable, biocompatible, and possess antibacterial properties.
  • The presence of amino groups enhances crystallinity and influences material properties.
  • These functionalized terpolymers show promise for applications requiring tailored surface properties and biological activity.