[Autoimmune/inflammatory syndrome induced by aduvants].

Area of Science:

• Immunology
• Rheumatology
• Plastic Surgery

Background:

• Silicone implants (SI) are widely used for breast reconstruction and augmentation.
• An estimated 1000-3000 women in Iceland have SI, with ~300 new procedures annually.
• No central registry exists in Iceland for silicone implant procedures.

Approach:

• This review synthesizes information from peer-reviewed sources in PubMed, UpToDate, and Scopus.
• It focuses on the Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) and silicone's immunological effects.
• Keywords include: silicone, immune response, autoimmunity, ASIA syndrome, and breast implant illness.

Key Points:

• The ASIA syndrome is a proposed condition linked to foreign materials like silicone.
• Potential immunological effects of silicone particles are discussed.
• The review examines symptoms, diagnosis, and statistical aspects of ASIA syndrome in relation to SI.

Conclusions:

• Further research is needed to fully understand the relationship between silicone implants and autoimmune diseases.
• Awareness of ASIA syndrome is crucial for patients and healthcare providers considering or managing SI.
• This review highlights the importance of monitoring and data collection for SI procedures.