SUBRETINAL FLUID ASSOCIATED WITH DRUSENOID PIGMENT EPITHELIAL DETACHMENT

Area of Science:

• Ophthalmology
• Retinal Diseases
• Medical Imaging

Background:

• Drusenoid pigment epithelial detachment (PED) is a significant finding in retinal diseases.
• Subretinal fluid (SRF) presence can influence the clinical course of PED.
• Understanding the impact of SRF on long-term outcomes is crucial for patient management.

Purpose of the Study:

• To analyze clinical characteristics of drusenoid PED with SRF.
• To evaluate the impact of SRF on long-term visual and anatomical outcomes in drusenoid PED.

Main Methods:

• Retrospective analysis of 47 eyes with drusenoid PED and >24 months follow-up.
• Comparison of visual and anatomical outcomes between eyes with and without SRF.
• Assessment of PED size, height, volume, visual acuity, and development of atrophy and neovascularization.

Main Results:

• Eyes with SRF had significantly larger PED height, diameter, and volume at baseline.
• No significant difference in best-corrected visual acuity at the final visit between groups.
• Similar incidence of complete retinal pigment epithelial and outer retinal atrophy (cRORA) and macular neovascularization (MNV) development.

Conclusions:

• PED size, height, and volume are associated with SRF development.
• SRF in drusenoid PED does not negatively affect long-term visual prognosis.
• SRF does not influence the development of macular atrophy in the long term.