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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
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Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
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Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
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Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

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The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
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Related Experiment Video

Updated: Aug 4, 2025

Imaging CD19+ B Cells in an Experimental Autoimmune Encephalomyelitis Mouse Model using Positron Emission Tomography
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Imaging CD19+ B Cells in an Experimental Autoimmune Encephalomyelitis Mouse Model using Positron Emission Tomography

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Positron Emission Tomography Imaging in Vasculitis.

Kornelis S M van der Geest1, Berend G C Slijkhuis2, Alessandro Tomelleri3

  • 1Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, the Netherlands.

Cardiology Clinics
|April 1, 2023
PubMed
Summary

[18F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT) is crucial for diagnosing and monitoring autoimmune blood vessel diseases. Advances in FDG-PET/CT technology enhance its ability to assess vasculitis extent and guide future immune cell-targeted imaging.

Keywords:
FDG-PET/CTHeartNovel tracersVasculitis

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Area of Science:

  • Immunology
  • Radiology
  • Nuclear Medicine

Background:

  • Systemic vasculitides are autoimmune diseases characterized by blood vessel inflammation.
  • Early and accurate diagnosis is essential for effective management and preventing complications.

Purpose of the Study:

  • To highlight the role of FDG-PET/CT in diagnosing and monitoring large- and medium-sized vessel vasculitides.
  • To discuss the impact of technological advancements on FDG-PET/CT's utility in vasculitis assessment.
  • To explore the potential of novel tracers for future diagnostic applications.

Main Methods:

  • Review of current literature on FDG-PET/CT in systemic vasculitides.
  • Discussion of the technical capabilities and limitations of FDG-PET/CT scanners.
  • Exploration of emerging imaging tracers for immune cell detection.

Main Results:

  • FDG-PET/CT is a valuable tool for diagnosing and monitoring large- and medium-sized vessel vasculitides.
  • Increasing scanner resolution and sensitivity improve the assessment of disease extent.
  • FDG-PET/CT offers complementary information compared to other vascular imaging modalities.

Conclusions:

  • FDG-PET/CT is integral to the management of systemic vasculitides.
  • Technological progress in FDG-PET/CT enhances diagnostic accuracy and disease monitoring.
  • Future developments in novel tracers promise more precise detection of vascular inflammation.