Related Experiment Video
Updated: Aug 4, 2025

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
Published on: November 13, 2016
Analyzing bursting synchronization in structural connectivity matrix of a human brain under external pulsed currents
Elaheh Sayari1, Enrique C Gabrick1, Fernando S Borges2
1Graduate Program in Science, State University of Ponta Grossa, 84030-900 Ponta Grossa, PR, Brazil.
Abstract:
Cognitive tasks in the human brain are performed by various cortical areas located in the cerebral cortex. The cerebral cortex is separated into different areas in the right and left hemispheres. We consider one human cerebral cortex according to a network composed of coupled subnetworks with small-world properties. We study the burst synchronization and desynchronization in a human neuronal network under external periodic and random pulsed currents. With and without external perturbations, the emergence of bursting synchronization is observed. Synchronization can contribute to the processing of information, however, there are evidences that it can be related to some neurological disorders. Our results show that synchronous behavior can be suppressed by means of external pulsed currents.

