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Periorbital Subcutaneous Perfluoron Is Well Tolerated Following Intravitreal Surgery
Ryan D Larochelle1, Ryan A Shields2, Benjamin P Erickson3
1Department of Ophthalmology, University of Colorado, Denver, CO, USA.
Purpose:
Perfluorocarbon liquids (PFCLs) are well tolerated in intraocular surgery, but chronic exposure can cause inflammation. PFCL leakage into the orbit without significant sequelae has been reported, but PFCL leakage into the preseptal subcutaneous tissues has not been described.
Methods:
A case report is presented.
Results:
A 46-year-old man presented with hand motion vision from a ruptured globe and retained intraocular foreign body. Intraoperatively, the foreign body could not be removed, and PFCL extravasated from the posterior globe rupture. Postoperative imaging revealed hyperdense material in the orbit, lids, and superficial adnexal tissues. The patient tolerated the retained PFCL, and imaging 10 months later demonstrated interval resorption. The patient eventually developed ocular siderosis and underwent transconjunctival orbitotomy with foreign body extraction. Two years following the initial injury, his vision remained stable at 20/40 without further sequelae.
Conclusions:
PFCL is well tolerated in the extraocular space and may resorb with conservative management.

