Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models01:06

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

102
Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
102
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

88
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
88
Maxwell-Boltzmann Distribution: Problem Solving01:20

Maxwell-Boltzmann Distribution: Problem Solving

1.6K
Individual molecules in a gas move in random directions, but a gas containing numerous molecules has a predictable distribution of molecular speeds, which is known as the Maxwell-Boltzmann distribution, f(v).
This distribution function f(v) is defined by saying that the expected number N (v1,v2) of particles with speeds between v1 and v2 is given by
1.6K
Gauss's Law: Problem-Solving01:10

Gauss's Law: Problem-Solving

1.8K
Gauss's law helps determine electric fields even though the law is not directly about electric fields but electric flux. In situations with certain symmetries (spherical, cylindrical, or planar) in the charge distribution, the electric field can be deduced based on the knowledge of the electric flux. In these systems, we can find a Gaussian surface S over which the electric field has a constant magnitude. Furthermore, suppose the electric field is parallel (or antiparallel) to the area...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Targeting NOX4 with Quercetagetin-PLGA nanomaterials: a novel therapeutic strategy for Alzheimer's disease.

Naunyn-Schmiedeberg's archives of pharmacology·2026
Same author

Defect engineering boosts CC bond cleavage for highly efficient ethylene glycol electrooxidation on Pd<sub>2</sub>Pb<sub>3</sub>Zn<sub>4</sub> intermetallic compound.

Journal of colloid and interface science·2026
Same author

Metabolomic Machine Learning Predictor for Adequate and Deep Response to UDCA in Non-Cirrhotic PBC.

Liver international : official journal of the International Association for the Study of the Liver·2026
Same author

The interplay between gastrointestinal dysfunction and gut microbiota dynamics in sepsis.

Frontiers in cellular and infection microbiology·2026
Same author

In vitro study on the synergistic effect of curcumin and PD98059 on anti-hepatocarcinoma and antitumor immune escape.

Cytotechnology·2026
Same author

Chemical composition of calcareous corpuscles in Echinococcus multilocularis protoscoleces.

Microbial pathogenesis·2026

Related Experiment Video

Updated: Aug 4, 2025

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
05:05

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

Published on: November 23, 2019

8.0K

Density-adaptive registration of pointclouds based on Dirichlet Process Gaussian Mixture Models.

Tingting Jia1,2, Zeike A Taylor3, Xiaojun Chen4,5

  • 1School of Biomedical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China.

Physical and Engineering Sciences in Medicine
|April 4, 2023
PubMed
Summary

We developed a robust algorithm for aligning pre- and intra-operative patient anatomy pointclouds in surgery. This method enhances augmented reality guidance by efficiently handling varying point densities and overlaps.

Keywords:
Density adaptiveDirichlet Process Gaussian mixture modelPointclouds registrationVariational Bayesian inference

More Related Videos

Measuring the Structure, Composition, and Change of Underwater Environments with Large-area Imaging
09:19

Measuring the Structure, Composition, and Change of Underwater Environments with Large-area Imaging

Published on: April 18, 2025

681
Optical Scatter Microscopy Based on Two-Dimensional Gabor Filters
14:58

Optical Scatter Microscopy Based on Two-Dimensional Gabor Filters

Published on: June 2, 2010

9.6K

Related Experiment Videos

Last Updated: Aug 4, 2025

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
05:05

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

Published on: November 23, 2019

8.0K
Measuring the Structure, Composition, and Change of Underwater Environments with Large-area Imaging
09:19

Measuring the Structure, Composition, and Change of Underwater Environments with Large-area Imaging

Published on: April 18, 2025

681
Optical Scatter Microscopy Based on Two-Dimensional Gabor Filters
14:58

Optical Scatter Microscopy Based on Two-Dimensional Gabor Filters

Published on: June 2, 2010

9.6K

Area of Science:

  • Medical Imaging
  • Computer Vision
  • Robotic Surgery

Background:

  • Accurate registration of pre- and intra-operative patient anatomy is crucial for augmented reality (AR) systems in minimally invasive surgery.
  • Existing methods struggle with variations in point density and spatial overlap between pre- and intra-operative pointclouds.

Purpose of the Study:

  • To propose a novel algorithm for robust rigid registration of patient anatomy pointclouds.
  • To improve the accuracy and efficiency of AR-guided surgical interventions.

Main Methods:

  • A probabilistic approach using a Dirichlet Process Gaussian Mixture Model (DPGMM) to represent transformed pointclouds.
  • Minimizing Kullback-Leibler divergence within a variational Bayesian inference framework.
  • Utilizing KDTrees for coarse-to-fine data and model expansion, with neighborhood-based scanning weights for robustness.

Main Results:

  • The proposed algorithm demonstrates comparable accuracy to existing Gaussian Mixture Model (GMM) methods.
  • Achieves higher computational efficiency compared to GMM methods, which are sensitive to the number of model components.
  • Exhibits robustness to variations in point density, noise, outliers, and spatial overlap.

Conclusions:

  • The DPGMM-based registration algorithm offers an efficient and robust solution for pre- and intra-operative pointcloud alignment.
  • This method facilitates the development of more reliable AR systems for surgical guidance.
  • The algorithm's ability to infer the optimal number of mixture components enhances its adaptability to diverse datasets.