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Stroke and cancer.

M Zuber1

  • 1Groupe hospitalier Paris Saint-Joseph, université Paris Cité, Paris, France.

Revue Neurologique
|April 6, 2023
PubMed
Summary
This summary is machine-generated.

Cancer patients face increased stroke risk, often due to hypercoagulation. Early detection and tailored treatments are crucial for improving outcomes in these complex cases.

Keywords:
CancerCancer-associated strokeHemorrhagic strokeHypercoagulabilityIschemic strokeOccult malignancy

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Area of Science:

  • Neurology
  • Oncology
  • Vascular Medicine

Background:

  • The association between cancer and stroke is well-documented, with increased risks for both ischemic and hemorrhagic stroke in cancer patients.
  • Approximately 5-10% of stroke patients have an active cancer diagnosis, with hematological malignancies and adenocarcinomas being most common.

Purpose of the Study:

  • To provide neurologists with practical insights into the stroke-cancer association.
  • To review stroke prevalence, mechanisms, diagnostic biomarkers, treatment influences, and prognosis in cancer patients.

Main Methods:

  • Review of current literature on stroke in cancer patients.
  • Discussion of diagnostic tools like Magnetic Resonance Imaging (MRI).
  • Analysis of acute and long-term treatment strategies and prognostic factors.

Main Results:

  • Hypercoagulation is a primary stroke mechanism in cancer patients, leading to thromboembolism.
  • MRI aids in identifying stroke patterns and differentiating hemorrhage types.
  • Intravenous thrombolysis appears safe in non-metastatic cancer patients; endovascular procedures show promise but higher reobstruction rates.

Conclusions:

  • Stroke prognosis is generally poorer in cancer patients, influenced by stroke severity and metastasis.
  • Understanding the stroke-cancer link is vital for optimizing patient management and outcomes.