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Updated: Aug 2, 2025

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
[Unruptured Intracranial Aneurysms:Endovascular Techniques and Devices:New Devices for Unruptured Intracranial
1Department of Neuroendovascular Therapy, Juntendo University, Graduate School of Medicine.
Abstract:
Factors causing the formation and growth of intracranial aneurysms include injury and congenital vulnerability of the arterial wall. Therefore, coil embolization of the saccular and fusiform components of intracranial aneurysms is not always curative, and the risk of recurrence in the long-term follow-up is high. Recently, flow diverters(e.g., pipeline, FRED, and Surpass Streamline)and an intrasaccular flow disruptor(W-EB)have been introduced as alternative embolic devices for intracranial aneurysms. These devices can repair arterial walls through neointimal formation surrounding the aneurysm neck and achieve complete cure. The PulseRider is a type of neck bride stent for bifurcation aneurysms that can effectively prevent coil herniation into the parent artery.
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