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Post-COVID Interstitial Lung Disease-The Tip of the Iceberg

Namrata Kewalramani1, Kerri-Marie Heenan2, Denise McKeegan2

  • 1Department for BioMedical Research DBMR, Inselspital, Bern University Hospital, University of Bern, Switzerland; Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Switzerland.

Immunology and Allergy Clinics of North America
|April 13, 2023
PubMed

Insights

Long COVID, a significant health burden, involves persistent symptoms after COVID-19 infection. This review examines emerging evidence on post-COVID interstitial lung disease, its mechanisms, and impact.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Pathophysiology

Background:

  • Post-COVID condition (long COVID) presents a substantial burden on patients and healthcare systems.
  • Understanding the long-term effects of COVID-19 is crucial for effective patient management.
  • Emerging respiratory complications require focused investigation.

Purpose of the Study:

  • To review the current evidence on the development of post-COVID interstitial lung disease.
  • To explore the pathophysiological mechanisms, incidence, and diagnostic approaches.
  • To assess the impact of this emerging respiratory condition.

Main Methods:

  • Systematic literature review of emerging evidence.
  • Analysis of pathophysiological mechanisms.
  • Evaluation of diagnostic criteria and incidence data.

Main Results:

  • Growing evidence suggests interstitial lung disease as a sequela of COVID-19.
  • Specific pathophysiological pathways are being identified.
  • Incidence and long-term impact data are still developing.

Conclusions:

  • Post-COVID interstitial lung disease is an emerging concern requiring further research.
  • Understanding its development is key to managing long-term respiratory health after COVID-19.
  • Early diagnosis and intervention strategies are needed.

Keywords:
COVID-19Interstitial lung diseaseLong-term impactPost-COVID fibrosisPost-COVID-19 condition (long COVID)

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