Hypereosinophilia, ulcerative colitis, sclerosing cholangitis, and bile duct carcinoma

A case of ulcerative colitis and pericholangitis-sclerosing cholangitis bile duct carcinoma complex associated with hypereosinophilia and possibly the hypereosinophilic syndrome is reported, and the association of eosinophilia with various hepatobiliary and gastrointestinal diseases is discussed. Hypereosinophilia may foretell a more serious underlying condition such as bile duct carcinoma in some patients with primary sclerosing cholangitis.