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Updated: Aug 2, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Electroreductive Nickel-Catalyzed Allylation of Aryl Chlorides
Xin Fu1, Tingting Ran1, Yu Zhou1
1College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
Abstract:
Herein, we report a facile and efficient allylation via electrochemical promoted Ni-catalyzed reductive carbon-carbon bond formation. Readily available (hetero)aryl chlorides with a variety of allylic sulfones are used as electrophiles in this electroreductive coupling. This Ni-catalyzed modular approach displays generally good functional group tolerance and broad substrate scope. This reaction allows a series of allylic compounds to be created including several structurally complex natural products and pharmaceutical motifs.
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