Related Experiment Video
Updated: Aug 2, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Organocatalytic photoinduced carboamination of dienes
Arun Yadav1,2, Sabhya Sandha1, Chandra Bhushan Tripathi1,2
1Medicinal & Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow-226031, India. chandra.tripathi@cdri.res.in.
Abstract:
An organocatalytic photoinduced 1,2-carbofunctionalization strategy for conjugated dienes has been developed. No exogenous photocatalyst or additives are required in this mild protocol and it allows for highly regioselective and efficient 1,2-carboisothiocyanation through the coupling of a diene, an alkyl radical and TMSNCS. The reaction is proposed to proceed through EDA complexation between the diene and TMSNCS.
Related Concept Videos
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Cycloaddition Reactions: MO Requirements for Photochemical Activation
Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry
Carboxylic Acids to Methylesters: Alkylation using Diazomethane

