Related Experiment Video
Updated: Aug 2, 2025
28:13
Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
33.5K
Left Atrial Thrombus-Are All Atria and Appendages Equal?
Alberto Cresti1, Oscar Camara2
1Cardiology Department, Misericordia Hospital, Azienda Sanitaria Toscana SudEst, Via Senese, Grosseto 58100, Italy.
Cardiac Electrophysiology Clinics
|April 19, 2023
Summary
The left atrial appendage (LAA), a common source of stroke, has variable anatomy hindering risk assessment. Advanced imaging and computational analysis can fully characterize LAA structure and function for personalized treatment.
Area of Science:
- Cardiology
- Medical Imaging
- Computational Anatomy
Background:
- The left atrial appendage (LAA) is implicated as a primary source of cardioembolic stroke.
- Significant morphological variability of the LAA complicates risk stratification for thrombosis.
- Quantitative assessment of LAA anatomy and function presents considerable challenges.
Purpose of the Study:
- To explore the critical, yet not fully understood, functions of the LAA.
- To address the challenges in defining LAA normality and stratifying thrombotic risk.
- To investigate advanced multimodality imaging and computational tools for comprehensive LAA characterization.
Main Methods:
- Utilizing a multimodality imaging approach.
- Employing advanced computational tools for data analysis.
- Focusing on quantitative metrics of LAA anatomy and function.
Main Results:
- Demonstrated the feasibility of comprehensive LAA characterization.
- Enabled individualized assessment of LAA morphology and function.
- Provided a pathway for personalized medical decisions in left atrial thrombosis.
Conclusions:
- Multimodality imaging combined with computational analysis offers a complete LAA characterization.
- This approach facilitates personalized medical decisions for patients with left atrial thrombosis.
- Understanding LAA variability is key to improving stroke risk stratification.
Related Concept Videos
01:16Chambers of the Heart
5.5K
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Deoxygenated blood from the body is received in the right...
5.5K
01:21Coronary Circulation
3.3K
The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
3.3K
01:24Cardiac Catheterization III: Left Heart Catheterization
105
Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
105
01:27Anatomy of the Heart
109.9K
The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
109.9K
01:30Venous Thrombosis I: Introduction
14
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
14
01:22Aortic Regurgitation II: Clinical Features and Diagnostic Tests
37
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
37