Hypertrophic Cardiomyopathy After Heart Transplantation: A Single-Center Case Series

Hans Gao1, Evan Kransdorf1, Joseph Ebinger1

  • 1Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

JACC. Case Reports
|April 20, 2023
PubMed

Insights

Three heart transplant patients developed hypertrophic cardiomyopathy years after their procedure. Diagnosis was confirmed using echocardiography and cardiac magnetic resonance imaging.

Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Cardiovascular Imaging

Background:

  • Heart transplantation is a life-saving procedure for end-stage heart failure.
  • Long-term complications after heart transplantation require ongoing monitoring.
  • Hypertrophic cardiomyopathy is a significant cardiac condition affecting heart muscle structure.

Observation:

  • Three cases of heart transplant recipients are presented.
  • These patients developed hypertrophic cardiomyopathy years post-transplantation.
  • The onset of cardiomyopathy occurred in the late post-transplant period.

Findings:

  • Diagnosis of hypertrophic cardiomyopathy was initially established via echocardiography.
  • Cardiac magnetic resonance imaging confirmed the diagnosis in all three cases.
  • The findings highlight a potential long-term complication following heart transplantation.

Implications:

  • This presentation suggests a possible association between heart transplantation and the development of hypertrophic cardiomyopathy.
  • Cardiovascular imaging, including echocardiography and MRI, plays a crucial role in diagnosing this complication.
  • Further research is warranted to understand the mechanisms and long-term outcomes of this condition in transplant recipients.

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