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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
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Updated: Aug 1, 2025

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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Atopic Dermatitis.

Karl T Clebak1, Leesha Helm1, Prabhdeep Uppal2

  • 1Department of Family and Community Medicine, Penn State Health Milton. S Hershey Medical Center, 500 University Drive, H154/C1613 Hershey, PA 17033, USA.

Primary Care
|April 27, 2023
PubMed
Summary
This summary is machine-generated.

Atopic dermatitis (AD) is a chronic inflammatory skin condition causing itchy, red lesions. Effective management focuses on reducing symptoms and skin changes through various treatments.

Keywords:
Atopic dermatitisEmollients and skin carePhototherapySystemic therapyTopical therapy

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Area of Science:

  • Dermatology
  • Immunology

Background:

  • Atopic dermatitis is a prevalent, chronic inflammatory skin condition.
  • It is characterized by recurrent episodes of erythematous, scaly, and pruritic lesions, typically on flexural surfaces.
  • The disease significantly impacts patient quality of life due to persistent itching and discomfort.

Purpose of the Study:

  • To outline the primary treatment objectives for atopic dermatitis.
  • To provide a comprehensive overview of current therapeutic strategies for managing atopic dermatitis.

Main Methods:

  • Review of existing literature on atopic dermatitis management.
  • Synthesis of information on various treatment modalities.

Main Results:

  • Treatment goals emphasize symptom alleviation, specifically reducing itching and burning sensations.
  • Skin changes associated with atopic dermatitis require targeted interventions.
  • A multi-modal treatment approach is essential for effective disease control.

Conclusions:

  • Comprehensive management of atopic dermatitis involves a combination of therapies.
  • Key treatment components include emollients, topical therapies (corticosteroids, steroid-sparing agents), systemic treatments, and phototherapy.
  • The goal is to achieve remission and improve the quality of life for individuals with atopic dermatitis.