Related Experiment Video
Updated: Aug 1, 2025

09:03
A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice
Published on: November 15, 2019
10.0K
Endophthalmitis in Silicone Oil-Filled Eyes
Magdalene Yin Lin Ting1, Soyang Ella Kim1, Rodrigo Anguita1,2
1Moorfields Eye Hospital NHS Foundation Trust, City Road, London EC1V 2PD, UK.
Antibiotics (Basel, Switzerland)
|April 28, 2023
Summary
Infectious endophthalmitis in silicone oil-filled eyes is rare, with guarded visual prognoses. Management involves antibiotics, sometimes with silicone oil removal, and further research is needed.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Post pars plana vitrectomy (PPV) endophthalmitis incidence ranges from 0.02% to 0.13%.
- Infectious endophthalmitis in silicone oil-filled eyes is a rarer complication.
Purpose of the Study:
- To review the incidence, risk factors, pathogens, management, and prognosis of infectious endophthalmitis in silicone oil-filled eyes.
- To provide a comprehensive resource for ophthalmologists managing this rare condition.
Main Methods:
- Literature review of studies on infectious endophthalmitis in silicone oil-filled eyes.
- Analysis of incidence, causative pathogens, management strategies, and visual outcomes.
Main Results:
- Commensals are common causative pathogens.
- Traditional management includes silicone oil (SO) removal and intravitreal antibiotics, or direct intravitreal antibiotics into SO-filled eyes.
- Visual prognoses are generally guarded.
Conclusions:
- Limited studies exist due to the condition's rarity, often with small sample sizes or retrospective designs.
- Observational studies and case reports are valuable for understanding rare conditions.
- Further research is needed to improve management and outcomes for infectious endophthalmitis in silicone oil-filled eyes.
Related Concept Videos
Glaucoma: Overview
648
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
648
Angle Closure Glaucoma: Treatment
587
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
587

