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Gold Nanoparticle Modified Carbon Fiber Microelectrodes for Enhanced Neurochemical Detection
Published on: May 13, 2019
Polymer nanofiber network reinforced gold electrode array for neural activity recording
Siting Yang1,2, Ke Xu1,2, Shouliang Guan1
1CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, 100190 China.
Abstract:
Flexible and stretchable neural electrodes are promising tools for high-fidelity interfacing with soft and curvilinear brain surface. Here, we describe a flexible and stretchable neural electrode array that consists of polyacrylonitrile (PAN) nanofiber network reinforced gold (Au) film electrodes. Under stretching, the interweaving PAN nanofibers effectively terminate the formation of propagating cracks in the Au films and thus enable the formation of a dynamically stable electrode-tissue interface. Moreover, the PAN nanofibers increase the surface roughness and active surface areas of the Au electrodes, leading to reduced electrochemical impedance and improved signal-to-noise ratio. As a result, PAN nanofiber network reinforced Au electrode arrays can allow for reliable in vivo multichannel recording of epileptiform activities in rats.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s13534-022-00257-5.

