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Updated: Jul 31, 2025
Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
Published on: May 2, 2013
Identifying risk factors for cutaneous disease among solid organ transplant recipients: A retrospective review
Chelsea Shope1, Laura Andrews1, Mary Nan Leath1
1College of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Background:
As solid organ transplant recipient (SOTR) life expectancy lengthens, the risk of developing other chronic diseases also increases.
Objective:
To determine the cutaneous pathologies for which SOTRs are at an increased risk.
Methods:
We performed a retrospective review of SOTRs seen by dermatology from January 1, 2012 and June 1, 2022. Data were analyzed using multivariate logistic regression. Benjamini Hochberg-adjusted P values were examined for multiplicity.
Results:
Five hundred and thirty SOTRs were identified. Patients had cutaneous malignancy (38.3%), precancerous lesions (32.5%), inflammatory (35.5%), and infectious diseases (33.1%). Odds of precancerous lesions were higher with increased age at transplant (odds ratio [OR], 1.04; adjusted P =.006), and lower with female sex (OR, 0.505; adjusted P =.006) and African American race (OR, 0.027; adjusted P =.006). Odds of inflammatory lesions were lower with increased age at transplant (OR, 0.979; adjusted P =.023). Odds of infectious diseases were higher with prednisone use (OR, 2.615; adjusted P value =.023).
Limitations:
This study is retrospective and was not able to capture patients seen by dermatology outside of our institution.
Conclusions:
SOTRs at risk of cutaneous lesions should be referred to dermatology because these conditions may place a significant burden on the quality of life.
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