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Updated: Jun 27, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

New Landscape for Atopic Dermatitis Therapies.

Stephanie Munie Waggett¹, Eric Sanfilippo¹, Milaan Shah¹

¹Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, SC, USA.

Pediatric Clinics of North America

|June 25, 2026

Summary

This summary is machine-generated.

Targeted therapies like biologics offer significant advancements in atopic dermatitis (AD) treatment, leading to high disease control. New guidelines reflect these effective and safe options, supplanting older systemic agents.

Keywords:

AD Atopic dermatitis Eczema Therapies

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Last Updated: Jun 27, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

Area of Science:

Dermatology
Immunology
Pharmacology

Background:

Atopic dermatitis (AD) management has seen significant evolution since 2014.
Traditional treatments include gentle skin care, emollients, and topical therapies.
Previous systemic agents are being replaced by newer, more effective options.

Purpose of the Study:

To discuss the evolving treatment landscape for atopic dermatitis.
To highlight the impact of targeted therapies, including biologics and small molecule inhibitors.
To provide insights into ongoing clinical trials for AD.

Main Methods:

Review of updated American Academy of Dermatology (AAD) guidelines (2023).
Analysis of the advent and impact of biologics and small molecule inhibitors.
Comparison of efficacy and safety profiles of new versus old systemic agents.

Main Results:

Targeted therapies achieve complete or near-complete resolution in AD patients.
Newer systemic agents demonstrate superior efficacy and safety compared to older treatments.
The foundation of AD care remains consistent, integrating new therapies.

Conclusions:

Biologics and small molecule inhibitors represent a revolution in AD treatment.
Updated guidelines reflect the superior outcomes of targeted therapies.
The field continues to advance with ongoing clinical research.