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OPTN/SRTR 2021 Annual Data Report: Heart
Monica M Colvin1, Jodi M Smith2, Yoon Son Ahn3
1Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN; Department of Cardiology, University of Michigan, Ann Arbor, MI.
Insights
Recent heart transplantation policies and the COVID-19 pandemic impacted patient care. Despite challenges, adult heart transplant rates increased, and pretransplant mortality declined for all ages.
Area of Science:
- Cardiology
- Transplantation Medicine
- Public Health
Background:
- The last five years presented significant challenges to heart transplantation.
- The 2018 policy revision and the COVID-19 pandemic influenced practices and outcomes.
Purpose of the Study:
- To analyze trends and impacts on heart transplantation over the past five years.
- To evaluate the effects of policy changes and the pandemic on heart transplant candidates and recipients.
Main Methods:
- Analysis of heart transplantation data from the past five years.
- Comparison of transplant rates, waiting list dynamics, and mechanical circulatory support use.
Main Results:
- Heart transplants increased overall in the US, but new candidates decreased during the pandemic.
- Transplant rates declined in pediatric candidates, especially infants, but increased in adults.
- Pretransplant mortality decreased for both pediatric and adult candidates.
- Use of ventricular assist devices increased in pediatric recipients; short-term mechanical support increased in adults.
Conclusions:
- Despite challenges, the field of heart transplantation shows resilience and advancement.
- Policy adjustments and evolving support strategies are shaping current and future heart transplant outcomes.
Abstract:
The past 5 years have posed challenges to the field of heart transplantation. The 2018 heart allocation policy revision was accompanied by anticipated practice adjustments and increased use of short-term circulatory support, changes that may ultimately serve to advance the field. The COVID-19 pandemic also had an impact on heart transplantation. While the number of heart transplants in the United States continued to increase, the number of new candidates decreased slightly during the pandemic. There were slightly more deaths following removal from the waiting list for reasons other than transplant during 2020, and a decline in transplants among candidates listed as status 1, 2, or 3 compared with the other statuses. Heart transplant rates decreased among pediatric candidates, most notably among those younger than 1 year. Despite this, pretransplant mortality has declined for both pediatric and adult candidates, particularly candidates younger than 1 year. Transplant rates have increased in adults. The prevalence of ventricular assist device use has increased among pediatric heart transplant recipients, while the prevalence of short-term mechanical circulatory support, particularly intra-aortic balloon pump and extracorporeal membrane oxygenation, has increased among adult recipients.
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