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Updated: Jul 31, 2025
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Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
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Metabolomics in acromegaly: a systematic review
Oana Pînzariu1, Carmen Emanuela Georgescu1,2
1Department of Endocrinology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Summary
Metabolomics reveals altered pathways in acromegaly, identifying specific metabolites like choline in pituitary tumors. This offers insights for personalized medicine to manage therapeutic response heterogeneity.
Area of Science:
- Endocrinology
- Metabolomics
- Oncology
Background:
- Acromegaly treatment response varies despite advances, necessitating personalized medicine.
- Metabolomics can elucidate molecular mechanisms behind treatment heterogeneity.
- Understanding altered metabolic pathways may improve acromegaly management.
Conclusions:
- Metabolomic profiling provides insights into acromegaly pathogenesis and therapeutic response heterogeneity.
- Specific metabolites and pathways identified may serve as biomarkers for disease management.
- Metabolomics supports the development of personalized medicine approaches for acromegaly.
