Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model01:09

Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model

352
Various dissolution theories provide insight into the factors that influence the dissolution rate. Danckwerts' Model suggests that turbulence, rather than a stagnant layer, characterizes the dissolution medium at the solid-liquid interface. In this model, the agitated solvent contains macroscopic packets that move to the interface via eddy currents, facilitating the absorption and delivery of the drug to the bulk solution. The regular replenishment of solvent packets maintains the...
352

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

pH-Responsive Core-Shell Polymer Capsules via Liquid-Liquid Encapsulation with Decoupled Release Onset and Diffusion Kinetics.

ACS applied bio materials·2026
Same author

Creating Tunable Low-Surface-Tension-Liquid Capsules via Impact-Driven Liquid-Liquid Encapsulation.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Alginate cryogel beads for effectively aggregating nanoplastics for water remediation.

Communications chemistry·2025
Same author

Solvent-Induced Triradial Pattern Formation on Solid-Supported Viscoelastic Thin Films and Gels.

ACS applied materials & interfaces·2025
Same author

Controlled Release of Dyes from Hydrogel Cargoes through pH and Magnetic Stimuli.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

Dynamics of an Artificial Tear Film on Contact Lenses in Response to a Moving Force Mimicking Fingertip Application.

ACS applied materials & interfaces·2025

Related Experiment Video

Updated: Jul 31, 2025

High Throughput Single-cell and Multiple-cell Micro-encapsulation
16:19

High Throughput Single-cell and Multiple-cell Micro-encapsulation

Published on: June 15, 2012

18.8K

Liquid-Liquid Encapsulation: Penetration vs. Trapping at a Liquid Interfacial Layer.

Sirshendu Misra1, Utsab Banerjee1, Sushanta K Mitra1

  • 1Micro & Nano-Scale Transport Laboratory, Waterloo Institute for Nanotechnology, Department of Mechanical and Mechatronics Engineering, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada.

ACS Applied Materials & Interfaces
|May 5, 2023
PubMed
Summary

We developed a fast liquid-liquid encapsulation method using droplet impingement. This technique creates stable capsules for protecting sensitive materials in harsh environments, offering versatile applications.

Keywords:
core−shell structuresdroplet impactinterfacial trappingliquid−liquid encapsulationpoly(dimethylsiloxane)

More Related Videos

Rapid Encapsulation of Reconstituted Cytoskeleton Inside Giant Unilamellar Vesicles
07:48

Rapid Encapsulation of Reconstituted Cytoskeleton Inside Giant Unilamellar Vesicles

Published on: November 10, 2021

4.4K
On-Chip Octanol-Assisted Liposome Assembly for Bioengineering
09:45

On-Chip Octanol-Assisted Liposome Assembly for Bioengineering

Published on: March 17, 2023

2.7K

Related Experiment Videos

Last Updated: Jul 31, 2025

High Throughput Single-cell and Multiple-cell Micro-encapsulation
16:19

High Throughput Single-cell and Multiple-cell Micro-encapsulation

Published on: June 15, 2012

18.8K
Rapid Encapsulation of Reconstituted Cytoskeleton Inside Giant Unilamellar Vesicles
07:48

Rapid Encapsulation of Reconstituted Cytoskeleton Inside Giant Unilamellar Vesicles

Published on: November 10, 2021

4.4K
On-Chip Octanol-Assisted Liposome Assembly for Bioengineering
09:45

On-Chip Octanol-Assisted Liposome Assembly for Bioengineering

Published on: March 17, 2023

2.7K

Area of Science:

  • Materials Science
  • Chemical Engineering
  • Colloid and Surface Science

Background:

  • Encapsulation is crucial for protecting sensitive cargo and controlling its release.
  • Existing liquid-liquid encapsulation methods can be slow or complex.
  • Ultrafast encapsulation (∼100 ms) is desirable for industrial applications.

Purpose of the Study:

  • To develop a robust and ultrafast liquid-liquid encapsulation framework.
  • To demonstrate a simple impingement-based method for creating stable capsules.
  • To explore the mechanisms and applications of this novel encapsulation technique.

Main Methods:

  • Utilizing droplet impingement of a core liquid onto an interfacial shell-forming liquid layer.
  • Employing poly(dimethylsiloxane) (PDMS) as a biocompatible and stable shell material.
  • Analyzing encapsulation pathways (necking-driven penetration vs. interfacial trapping) based on kinetic energy and thermodynamics.

Main Results:

  • Achieved stable liquid-liquid encapsulation via a simple, impact-driven method.
  • Demonstrated two distinct encapsulation pathways, both leading to successful core protection.
  • Showcased the protection of immiscible liquids (honey/maple syrup in water) and the creation of multifunctional compound droplets.
  • Successfully heat-cured and extracted robust capsules, confirming practical utility.

Conclusions:

  • The developed impingement-based method provides a versatile and ultrafast approach to liquid-liquid encapsulation.
  • The technique is minimally restrictive and kinetic energy independent, enabling broad applicability.
  • The resulting capsules offer excellent protection for vulnerable cores and can be functionalized for specific applications.