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Routine Screening Method for Microparticles in Platelet Transfusions

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Published on: January 31, 2018

High red cell distribution width-to-platelet ratio indicates adverse outcomes for hepatitis B virus-associated

Qiu Zhang¹, WeiLin Mao², Xia He¹

¹Department of Clinical Laboratory, Shengzhou People's Hospital, Shengzhou Branch of the First Affiliated Hospital of Zhejiang University, Shengzhou, 312400, China.

Biomarkers in Medicine

|May 9, 2023

Abstract:

Background: This work was designed to determine the association between red cell distribution width-to-platelet ratio (RPR) and 30-day prognosis in hepatitis B virus-associated decompensated cirrhosis (HBV-DC) patients. Methods: A total of 168 HBV-DC patients were included. Independent risk factors for poor prognosis were determined by logistic regression analyses. Results: A total of 21 (12.5%) patients died within 30 days. RPR was higher in nonsurvivors than in survivors. Multivariate analysis identified RPR and Model for End-Stage Liver Disease (MELD) score as independent prognostic predictors, and the predictive value of RPR was similar to that of the MELD score. Moreover, combining RPR with the MELD score further improved the predictive value for mortality. Conclusion: RPR has potential as a reliable tool for the prediction of poor prognosis in HBV-DC patients.

Keywords:

RDW RPR decompensated cirrhosis hepatitis B virus mortality predictor

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