Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Not a Mollusc! A Case Report about the Subepidermal Calcified Nodule of Winer.

Klinische Monatsblatter fur Augenheilkunde·2026
Same author

From Lymph Nodes to Orbit: a Time Travel in IgG4-related Disease.

Klinische Monatsblatter fur Augenheilkunde·2026
Same author

[Outcome of Congenital Obstruction of the Nasolacrimal Duct].

Klinische Monatsblatter fur Augenheilkunde·2025
Same author

Assessment of potential myopia risk factors, including chronotype, in Estonian adolescents: a cross-sectional study.

BMC ophthalmology·2024
Same author

Future treatment options for facial nerve palsy: a review on electrical stimulation devices for the orbicularis oculi muscle.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2023
Same author

Surgical Procedure and Perioperative Management of a Giant Orbital Echinococcus Cyst during and after Pregnancy.

Klinische Monatsblatter fur Augenheilkunde·2023

Related Experiment Video

Updated: Jul 31, 2025

A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration
09:24

A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration

Published on: March 10, 2023

1.7K

Retinal Periphlebitis May Be a Marker for Subphenotype in Multiple Sclerosis.

Reili Rebane1, Katrin Sonajalg1, Kaarel Kree2

  • 1Department of Ophthalmology, East Tallinn Central Hospital, Tallinn, Estonia.

Klinische Monatsblatter Fur Augenheilkunde
|May 10, 2023
PubMed
Summary
This summary is machine-generated.

Retinal periphlebitis (RPP) in multiple sclerosis (MS) patients may indicate distinct immunopathology. Early retinal exams in MS patients are crucial for identifying RPP and potentially guiding treatment decisions.

More Related Videos

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.3K
Author Spotlight: Unraveling the Pathogenesis of Age-Related Macular Degeneration and Discovering Potential Therapies
06:16

Author Spotlight: Unraveling the Pathogenesis of Age-Related Macular Degeneration and Discovering Potential Therapies

Published on: July 28, 2023

2.6K

Related Experiment Videos

Last Updated: Jul 31, 2025

A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration
09:24

A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration

Published on: March 10, 2023

1.7K
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.3K
Author Spotlight: Unraveling the Pathogenesis of Age-Related Macular Degeneration and Discovering Potential Therapies
06:16

Author Spotlight: Unraveling the Pathogenesis of Age-Related Macular Degeneration and Discovering Potential Therapies

Published on: July 28, 2023

2.6K

Area of Science:

  • Ophthalmology
  • Neurology
  • Immunology

Background:

  • Retinal periphlebitis (RPP) is a known complication in multiple sclerosis (MS).
  • Recent advances in MS pathogenesis and heterogeneity warrant a re-evaluation of RPP.
  • RPP's role in MS has not been extensively studied in light of new developments.

Purpose of the Study:

  • To investigate retinal periphlebitis (RPP) in contemporary multiple sclerosis (MS) patients.
  • To explore the potential of RPP as a marker for MS subphenotypes.
  • To understand the immunopathological implications of RPP in MS.

Main Methods:

  • Case series presentation of six MS patients with RPP.
  • Clinical evaluation including ophthalmological examinations.
  • Analysis of RPP in the context of MS characteristics and potential immunopathology.

Main Results:

  • Six cases of RPP were identified in relapsing-remitting MS patients (3 female, 3 male).
  • Most patients had minimal or no ocular symptoms, highlighting the need for thorough retinal screening.
  • RPP involvement suggests potential distinct autoantigenic targets in MS immunopathology.

Conclusions:

  • Retinal periphlebitis may be an underdiagnosed sign in MS patients, even with minor ocular symptoms.
  • RPP could serve as a valuable subphenotype marker in MS, potentially influencing therapeutic strategies.
  • Further research is essential to elucidate the full impact and implications of RPP in MS.