Palladium-catalyzed disilylation of ortho-halophenylethylenes enabled by 2-pyridone ligand
Bin-Bin Zhu1, Shu-Sheng Zhang2, Jian-Guo Fu2
1CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200032, China.
Abstract:
A palladium-catalyzed disilylation reaction applicable for a variety of non-, α-, or β-substituted and α,β-disubstituted ortho-halophenylethylenes has been developed. This reaction proceeds with high yields and very low catalyst loadings. The two C-Si bonds of the disilylated products could be well-differentiated chemoselectively in the reaction with various electrophiles.
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