Chitosan-Based Polymer Blends for Drug Delivery Systems.

Area of Science:

• Biomaterials Science
• Polymer Chemistry
• Pharmaceutical Sciences

Background:

• Polymers are crucial for controlled drug delivery, enabling consistent dosing and adjustable release of various drugs.
• Polymer blends offer superior performance over homopolymers in drug development.
• Chitosan, a versatile biopolymer, is being explored in blends to improve its inherent properties for drug delivery applications.

Purpose of the Study:

• To review recent research on chitosan blends for enhanced drug delivery systems.
• To explore the diverse applications of chitosan blends in pharmaceutical formulations.
• To highlight the advantages of chitosan-based nanocarriers in therapeutic delivery.

Main Methods:

• Literature review of research published in the past ten years.
• Data compilation from scientific databases (ScienceDirect, J-Gate, Google Scholar, PubMed).
• Analysis of novel nanocarrier systems utilizing chitosan blends.

Main Results:

• Chitosan blends demonstrate improved properties compared to pure chitosan.
• Nanocarriers derived from chitosan blends exhibit a positive surface charge, enabling controlled drug release kinetics.
• These advanced systems facilitate controlled rate, duration, and site-specific drug delivery.

Conclusions:

• Chitosan blends represent a promising strategy for developing advanced drug delivery systems.
• Chitosan-based nanocarriers offer enhanced safety, efficacy, and prolonged drug release.
• The cost-effectiveness and versatility of chitosan blends make them suitable for various dosage forms.