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Child With Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue

Khalid A Alghamdi1, Alaa M Bokhari1, Imad A El Hag2

  • 1From the Pediatric Department, Security Forces Hospital, Riyadh, Saudi Arabia.

JPGN Reports
|May 19, 2023
PubMed

Insights

Helicobacter pylori infection can lead to gastric lymphoma, even in children. Upper gastroscopy is crucial for diagnosing this serious condition in young patients with nonspecific symptoms.

Area of Science:

  • Pediatric Gastroenterology
  • Oncology
  • Infectious Diseases

Background:

  • Nonspecific gastrointestinal symptoms are common in children with Helicobacter pylori infection.
  • Current guidelines recommend upper gastroscopy for diagnosing the cause of these symptoms.

Observation:

  • A 9-year-old girl presented with symptoms attributed to H. pylori infection.
  • Upper gastroscopy revealed gastric mucosa-associated lymphoid tissue (MALT) lymphoma.

Findings:

  • The patient was diagnosed with gastric MALT lymphoma, a rare condition in pediatric cases.
  • The lymphoma was directly associated with H. pylori infection.

Implications:

  • This case underscores the importance of upper gastrointestinal endoscopy in evaluating pediatric H. pylori infections.
  • Early diagnosis of H. pylori-associated gastric MALT lymphoma in children is critical for timely intervention.

Keywords:
Helicobacter pyloriMALTomaMucosa-associated lymphoid tissue lymphoma

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