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Knowledge mapping of immune thrombocytopenia: a bibliometric study
Feifeng Wu1, Cuifang Li1, Jueyi Mao1
1Department of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Frontiers in Immunology
|May 19, 2023
Summary
This bibliometric analysis reveals key trends and hotspots in immune thrombocytopenia (ITP) research. It highlights evolving areas like novel therapies, pathogenesis, and the impact of COVID-19 vaccines on ITP.
Area of Science:
- Immunology and Hematology
- Medical Research Methodology
Background:
- Immune thrombocytopenia (ITP) is an autoimmune disorder causing low platelet counts.
- Recent research focuses on ITP pathophysiology and novel therapeutic agents.
- Bibliometrics analyzes publication data to identify research trends and hotspots.
Purpose of the Study:
- To provide insights into developing trends and research hotspots in Immune Thrombocytopenia (ITP) using bibliometric analysis.
- To map the intellectual structure and evolution of ITP research.
Main Methods:
- Bibliometric analysis of 3299 publications on ITP.
- Utilized bibliometrix R package, VOSviewer, and CiteSpace for data analysis.
- Performed keyword co-occurrence and reference co-citation analyses.
Main Results:
- Identified 4 clusters related to ITP diagnosis, pathophysiology, and treatment.
- Discovered 5 major research trends: second-line treatment, chronic ITP, novel therapy, pathogenesis, and COVID-19 vaccine impact.
- Highlighted emerging hotspots: Treg cells, spleen tyrosine kinase, and mesenchymal stem cells.
Conclusions:
- This bibliometric analysis offers a comprehensive overview of ITP research.
- It identifies current hotspots and future research directions in the field of ITP.
- The findings enrich the understanding and review of ITP research literature.
