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[Gluteal granuloma in an infant]
Insights
Topical fluorinated steroid treatment for infant diaper dermatitis can lead to granulomatous nodules. These steroid-induced lesions in infants resolved after discontinuing the medication.
Area of Science:
- Dermatology
- Pediatrics
- Histopathology
Background:
- Infant diaper dermatitis is common and often treated with topical corticosteroids.
- Prolonged or potent steroid use can have adverse effects, particularly in infants.
Abstract:
This report deals with a 5-month-old infant who at the age of 2 months was treated with topical fluorinated steroids for dermatitis in the diaper area. The treatment was continued for about 2 months. Some weeks later, multiple oval and round dark brown nodules developed in the inguinogenital areas. Histologic examination of these lesions revealed intense granulomatous infiltration in the upper dermis that consisted of lymphocytes, neutrophilic and eosinophilic granulocytes, and histiocytes. After steroid therapy was discontinued, the nodules slowly disappeared.