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Crystal-storing histiocytosis and associated marginal zone lymphoma with extensive plasmacytic differentiation
Ayah Al-Qaderi1, Ali Sakhdari1
1Department of Laboratory Medicine and Pathobiology Toronto General Hospital, University Health Network Toronto Ontario Canada.
Abstract:
Crystal-storing histiocytosis (CSH) is a non-neoplastic histiocytic proliferation that results from the intra-lysosomal accumulation of immunoglobulins as crystals. CSH is frequently associated with various B-cell lymphomas or plasma cell neoplasms. CSH can potentially obscure underlying lymphoproliferative neoplasms. This association should always be considered and the tissue should be carefully evaluated.
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