Indocyanine green angiography-guided thyroidectomy versus conventional thyroidectomy for preserving parathyroid...

Area of Science:

• Endocrinology
• Surgical Oncology
• Medical Imaging

Background:

• Preserving parathyroid gland vascularization during thyroidectomy is crucial to prevent permanent hypoparathyroidism.
• Current thyroidectomy techniques may not consistently ensure adequate parathyroid gland blood supply.
• Indocyanine green (ICG) fluorescence angiography offers a potential method to visualize vascular patterns intraoperatively.

Purpose of the Study:

• To assess the efficacy and safety of ICG angiography-guided thyroidectomy in identifying parathyroid gland vascularization compared to conventional thyroidectomy.
• To determine if ICG angiography can reduce the rate of permanent hypoparathyroidism following total thyroidectomy.

Main Methods:

• A randomized, single-blind, multicenter clinical trial comparing ICG angiography-guided thyroidectomy with conventional thyroidectomy.
• Patients randomized 1:1 to either group; experimental group receives pre- and post-thyroidectomy ICG angiography.
• Primary outcome: rate of permanent hypoparathyroidism; secondary outcomes include post-op hypoparathyroidism, gland vascularization, iPTH, and calcium levels.

Main Results:

• (Study ongoing - results pending)
• (Study ongoing - results pending)
• (Study ongoing - results pending)

Conclusions:

• (Study ongoing - conclusions pending)
• (Study ongoing - conclusions pending)