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Updated: Jul 29, 2025
Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers
Published on: May 5, 2016
A multifunctionally reversible detector: Photoacoustic and dual-channel fluorescence sensing for SO2/H2O2
Yicai Zhu1, Junjun Wang1, Yingyong Ni1
1School of Chemistry and Chemical Engineering, Center of Free Electron Laser & High Magnetic Field, Anhui University, Hefei, 230601, PR China; Key Laboratory of Structure and Functional Regulation of Hybrid Materials (Anhui University) Ministry of Education, Hefei, 230601, PR China; Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, Hefei, 230601, PR China; Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials of Anhui Province, Hefei, 230601, PR China.
Abstract:
In this work, the phenothiazine fragment with powerful electron-donating ability was specifically selected to construct a multifunctional detector (noted as T1) in double-organelle with near-infrared region I (NIR-I) absorption. The changes of SO2/H2O2 content in mitochondria and lipid droplets were observed through red/green channels respectively, which was due to the reaction between benzopyrylium fragment of T1 and SO2/H2O2 to achieve red/green fluorescence conversion. Additionally, T1 was endowed with photoacoustic properties deriving from NIR-I absorption to reversibly monitor SO2/H2O2in vivo. This work was significant for more accurately deciphering the physiological and pathological processes in living organisms.
