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Association between food-based dietary inflammatory potential and ulcerative colitis: a case-control study.
Zeinab Khademi1,2, Parvane Saneei3, Ammar Hassanzadeh-Keshteli4,5
1Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. zeinabkhademi2121@gmail.com.
Scientific Reports
|May 25, 2023
Summary
This study found no link between a pro-inflammatory diet and ulcerative colitis (UC) risk in Iranian adults. Further research is needed to confirm this association between diet and UC.
Area of Science:
- Nutrition Science
- Gastroenterology
- Epidemiology
Background:
- Dietary inflammatory potential is linked to various health conditions.
- Limited research exists on the association between pro-inflammatory diets and ulcerative colitis (UC).
Purpose of the Study:
- To investigate the association between food-based dietary inflammatory potential (FDIP) and the odds of developing UC in Iranian adults.
Main Methods:
- A case-control study involving 109 UC patients and 218 healthy controls.
- Dietary data collected via a validated 106-item semi-quantitative food frequency questionnaire (FFQ).
- FDIP scores calculated based on intakes of 28 pre-defined food groups.
Main Results:
- No significant association was found between FDIP score and UC in crude (OR 0.93; 95% CIs 0.53-1.63) or multivariate models (OR 1.12; 95% CIs 0.46-2.71).
- The median FDIP scores for cases and controls were -1.36(3.25) and -1.54(3.15), respectively.
Conclusions:
- The study did not observe a significant association between a pro-inflammatory diet and the risk of UC.
- Prospective cohort studies are recommended to further explore the relationship between diet and UC.
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