Hidradenitis Suppurativa

Area of Science:

• Dermatology
• Chronic inflammatory skin conditions

Background:

• Hidradenitis suppurativa (HS) is a chronic, debilitating follicular disease.
• It presents with recurrent painful abscesses and sinus tracts, primarily in intertriginous zones.
• HS disproportionately impacts individuals of African-American heritage in the United States, affecting mental health and quality of life.

Purpose of the Study:

• To review the clinical presentation and diagnostic criteria for HS.
• To discuss current and emerging treatment targets for HS.
• To emphasize the specific considerations for HS in patients with skin of color.

Main Methods:

• Literature review of HS pathophysiology, clinical presentation, diagnosis, and treatment.
• Focus on studies and clinical observations relevant to skin of color.
• Synthesis of current understanding and future research directions.

Main Results:

• HS diagnosis relies on clinical presentation, including characteristic lesions and locations.
• Treatment strategies vary based on disease severity, including medical and surgical options.
• Understanding HS in skin of color is crucial due to potential diagnostic and therapeutic disparities.

Conclusions:

• HS is a significant health concern, particularly within the Black population.
• Early diagnosis and tailored treatment are essential for managing HS effectively.
• Further research is needed to address the specific needs of patients with HS and skin of color.