Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Affinity and Avidity

Affinity and Avidity

Affinity Chromatography

Affinity Chromatography

Affinity chromatography is a powerful technique extensively utilized for separating and purifying specific biomolecules from complex mixtures. It capitalizes on the highly selective binding between an analyte and its counterpart, such as antibody-antigen interactions. The counterpart is immobilized on the stationary phase, forming an affinity column. The stationary phase typically consists of solid support, such as agarose or porous glass beads, immobilizing the affinity ligand. The mobile...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Programming Dimensional Transitions in DNA Brick Crystals via Interfacial Connectivity.

Angewandte Chemie (International ed. in English)·2026

Same author

Structure-Controlled Molecular Recognition and Charge Transport in Metallized DNA Nanosheets.

Journal of the American Chemical Society·2026

Same author

Author Correction: Atomically precise photothermal nanomachines.

Nature materials·2026

Same author

L-DNA-Based Framework Nucleic Acid Nanodevice for Lysosomal ATP Imaging.

Analytical chemistry·2026

Same author

DNA-Programmed Amorphous PtCu Nanohybrids With Spatially Partitioned Functions for Hydrogen Evolution.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

DNA Framework Nucleator-Enabled Intelligent Hydrogel Interfaces on Living Cells.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

One-dimensional carbon chains free of end-capping groups.

Nature chemistry·2026

Same journal

Covalency control of photomagnetic relaxation in a manganese(II) photoswitch.

Nature chemistry·2026

Same journal

Trefoil polymers from a knotted synthon.

Nature chemistry·2026

Same journal

Inverted metal-free active template synthesis of rotaxanes via axle‑mediated macrocyclization.

Nature chemistry·2026

Same journal

Serendipitous twist in a hemithioindigo molecular motor enables energy storage.

Nature chemistry·2026

Same journal

Concise synthesis and strain-release diversification of bridgehead-substituted [2]-ladderanes.

Nature chemistry·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 28, 2025

Primer-Free Aptamer Selection Using A Random DNA Library

Primer-Free Aptamer Selection Using A Random DNA Library

Published on: July 26, 2010

Selecting aptamers with programmed affinities

Ping Song¹, Chunhai Fan^2,3

¹School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China. songpingsjtu@sjtu.edu.cn.

Nature Chemistry

|May 29, 2023

Summary

No abstract available in PubMed .

More Related Videos

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses

Published on: September 7, 2022

Related Experiment Videos

Last Updated: Jul 28, 2025

Primer-Free Aptamer Selection Using A Random DNA Library

Primer-Free Aptamer Selection Using A Random DNA Library

Published on: July 26, 2010

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses

Published on: September 7, 2022