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Outcome in Pediatric Functional Tic Disorders Diagnosed During the COVID-19 Pandemic
Alexander Mathew1, Amal Abu Libdeh1, James Patrie1
1School of Medicine (Mathew), Department of Neurology (Abu Libdeh, Garris), Public Health Sciences (Patrie), and Department of Pediatrics (Garris), University of Virginia, Charlottesville; Faculty of Medicine, Al-Balqa Applied University, Salt, Jordan (Abu Libdeh).
Pediatric functional tics improved for most patients post-diagnosis during COVID-19, but resolution was rare. Early diagnosis of these tics is crucial for better outcomes.
Area of Science:
- Neurology
- Pediatrics
- Psychiatry
Background:
- Pediatric functional tics increased during the COVID-19 pandemic.
- Prognosis for these cases remains poorly understood.
Purpose of the Study:
- To examine the clinical course of pediatric functional tics diagnosed during the pandemic.
- To identify factors influencing the prognosis of functional tics.
Main Methods:
- Retrospective review of 29 pediatric patients diagnosed with functional tics (March 2020-December 2021).
- Assessment of Clinical Global Impression-Improvement (CGI-I) scores and telephone interviews with 20 dyads.
- Logistic regression analysis to identify predictors of clinical outcomes.
Main Results:
- 82% of patients reported improvement, with a median CGI-I score of 2 (much improved).
- Median time to diagnosis was 197 days; symptom reduction occurred within 21 days post-diagnosis.
- Greater age and longer time to diagnosis were associated with decreased odds of improvement within one month.
Conclusions:
- Most pediatric functional tics cases showed improvement but not full resolution after diagnosis.
- Early diagnosis appears critical for improving functional tic symptoms in children.
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