[Toxicologic research on acute poisoning with fenitrothion (Agria 1050) in chickens]

An experiment was carried out with a total of 48 chickens, aged 11 months, and divided into 8 groups. The first two groups were kept as controls, and the remaining groups ere treated with phenitrothion as follows: III--100 mg/kg; IV--200 mg/kg; V--300 mg/kg; VI--500 mg/kg; VII--700 mg/kg; and VIII--800 mg/kg. It was found that the disease ran its course with characteristic clinical signs--laboured respiration of higher rate and dullness. Most characteristic were the drop of cholinesterase activity up to 71 per cent and the rise of blood sugar by 49 per cent. The clinical symptoms were found to correlate with the decrease in cholinesterase activity of blood plasma.