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Related Concept Videos

Diabetes: Management and Pharmacotherapy01:15

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The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Updated: Jul 27, 2025

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
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Study protocol: BRInging the Diabetes prevention program to GEriatric Populations.

Jeannette M Beasley1,2, Emily A Johnston2, Mary Ann Sevick2,3

  • 1Department of Nutrition and Food Studies, New York University, New York, NY, United States.

Frontiers in Medicine
|June 5, 2023
PubMed
Summary
This summary is machine-generated.

The Diabetes Prevention Program (DPP) shows older adults benefit from lifestyle interventions. This study compares in-person and virtual DPP delivery for geriatric populations to improve prediabetes management.

Keywords:
diabetes preventionimplementation sciencelifestyle changenutritionolder adultsphysical activitysocial supportvirtual

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Area of Science:

  • Geriatric Medicine
  • Preventive Cardiology
  • Public Health Interventions

Background:

  • The Diabetes Prevention Program (DPP) demonstrated significant diabetes risk reduction in older adults through intensive lifestyle interventions.
  • Despite proven efficacy, participation in the National DPP among American adults aged 65 and older with prediabetes remains low.
  • There is a critical need to adapt and deliver evidence-based diabetes prevention programs to this growing demographic.

Purpose of the Study:

  • To compare the effectiveness and implementation of an in-person DPP program tailored for older adults (DPP-TOAT) versus a virtual delivery model (V-DPP-TOAT).
  • To assess 6-month weight loss as the primary effectiveness outcome and intervention session attendance as the primary implementation outcome.
  • To inform optimal delivery strategies for evidence-based lifestyle interventions in geriatric populations.

Main Methods:

  • The BRInging the Diabetes prevention program to GEriatric Populations (BRIDGE) trial is a randomized controlled trial involving 230 participants.
  • Participants are recruited via electronic health records and randomized to either the in-person DPP-TOAT or the V-DPP-TOAT arm.
  • A non-inferiority design is employed to compare the two delivery methods.

Main Results:

  • Primary effectiveness outcome: 6-month weight loss.
  • Primary implementation outcome: Intervention session attendance.
  • The study will provide data on the comparative success of in-person versus virtual delivery.

Conclusions:

  • Findings will guide the development of best practices for delivering the DPP to older adults.
  • This research aims to enhance the accessibility and engagement of geriatric populations in diabetes prevention efforts.
  • Successful implementation of tailored DPP models can address the high prevalence of prediabetes in older Americans.