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Updated: Jul 27, 2025
A Preterm Rat Model for Pain Studies
Published on: February 9, 2024
A Systematic Review of Multisensory Stimulation on Procedural Pain Among Preterm Neonates
Neha Sharma1, Asir John Samuel
1Department of Pediatric and Neonatal Physiotherapy (Ms Sharma and Dr Samuel), Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation, Maharishi Markandeshwar (Deemed to be University), Mullana, Haryana, India; Yenepoya Physiotherapy College (Dr Samuel), Yenepoya (Deemed to be University), Mangalore, Karnataka, India.
Purpose:
This systematic review aims to evaluate the quality of studies and synthesize the literature on multisensory stimulation (MSS) on procedural pain among hospitalized preterm neonates.
Summary Of Key Points:
Search strategies were applied to PubMed/Medline, CINAHL, SCOPUS, and PEDro. A total of 414 studies were identified, 104 were screened, and 4 were included. Two independent reviewers extracted data from identified studies that were synthesized qualitatively and quantitatively.
Conclusion And Recommendations For Clinical Practice:
There is strong evidence of MSS in decreasing procedural pain, but additional research is needed to identify the beneficial effects of MSS with a standardized protocol to promote good clinical practice in neonatal intensive care settings.
What This Adds To The Evidence:
High-quality evidence supports beneficial effects of MSS, but standardization of the MSS protocol and its administration needs to be established.
