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DNA CONTENTS IN PURKINJE CELLS AND INNER GRANULE NEURONS IN THE DEVELOPING RAT CEREBELLUM
Setsuya Fujita1, Takanori Hattori1, Masaru Fukuda1
1Department of Pathology, Kyoto Prefectural University of Medicine, Kawaramachi, Kyoto 602, Japan.
Development, Growth & Differentiation
|June 7, 2023
Abstract:
Cytophotometric studies revealed that the content of Feulgen DNA in Purkinje cells in the developing rat cerebellum remains at the diploid level throughout the postnatal life. No evidence was found to suggest resumption of DNA synthesis in the neurons. This finding is in accord with autoradiographic observations that neuroblasts once differentiated from matrix cells do not synthesize DNA nor divide again.

