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EB 33, an epithelial cell line from human prostate carcinoma: a review
National Cancer Institute Monograph
|December 1, 1978
Summary
The EB 33 cell line, derived from human prostate adenocarcinoma, has been extensively characterized. This review covers its morphologic, biochemical, and immunologic properties, highlighting its value for prostate cancer research.
Area of Science:
- Oncology
- Cell Biology
- Immunology
Background:
- The EB 33 cell line was established from a human prostate adenocarcinoma in 1973.
- Extensive characterization efforts have been undertaken by multiple research laboratories.
- There is a significant demand for well-defined prostate cancer cell lines for immunological studies.
Purpose of the Study:
- To provide a comprehensive review of the EB 33 cell line.
- To consolidate existing data on its characterization.
- To emphasize its utility in immunological research.
Main Methods:
- Morphologic characterization.
- Biochemical analysis.
- Endocrinologic profiling.
- Genetic assessment.
- Immunologic parameter evaluation.
Main Results:
- The EB 33 cell line has undergone detailed investigation across various scientific domains.
- Data from multiple laboratories contribute to its comprehensive profile.
- Its suitability for immunological experimentation is a key finding.
Conclusions:
- The EB 33 cell line is a valuable and well-characterized resource.
- Its multifaceted characterization supports its use in diverse research applications.
- It serves as a crucial model for prostate cancer immunology research.