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Risk factors of multidrug-resistant bacteria infection in patients with ventilator-associated pneumonia: A systematic

Jian-Nan Hu1, Sheng-Qi Hu2, Zi-Ling Li1

  • 1Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
|June 15, 2023
PubMed
Abstract

Insights

Multidrug-resistant bacteria in ventilator-associated pneumonia (VAP) are deadly. This review identified 10 risk factors, including prior antibiotic use and longer hospital stays, to aid in VAP treatment and prevention.

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Epidemiology

Background:

  • Ventilator-associated pneumonia (VAP) caused by multidrug-resistant (MDR) bacteria presents a significant clinical challenge with high mortality rates.
  • Identifying risk factors for MDR bacterial infections in VAP is crucial for effective management and prevention strategies.

Conclusions:

  • This study successfully identified 10 significant risk factors contributing to MDR bacterial infections in VAP.
  • The findings provide valuable insights for clinicians to better target prevention efforts and optimize treatment strategies for VAP patients at risk of MDR infections.
Keywords:
Meta-analysisMulti-drug resistant bacteriaRisk factorsSystematic reviewVentilator associated pneumonia

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