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Clinical Recommendations for Augmentation Agents in Obsessive-Compulsive Disorder Partially Responsive to Serotonin

Mohan Gautam1

  • 1From the Beaumont Psychiatry, Beaumont Health, Southfield; Department of Psychiatry; Michigan State University, East Lansing; Wayne State University, Detroit; Oakland University William Beaumont, Dearborn, MI.

Journal of Clinical Psychopharmacology
|June 19, 2023
PubMed
Summary

For adults with obsessive-compulsive disorder (OCD) partially responding to serotonin reuptake inhibitors (SRIs), lamotrigine, memantine, and aripiprazole show the most promise as augmentation agents. Risperidone is a potential alternative if aripiprazole is not tolerated.

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