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A Multimodality Electrochemical and Impedance Spectroscopy System-on-a-Chip With Temperature Sensing and
IEEE Transactions on Biomedical Circuits and Systems
|June 20, 2023
Summary
This study introduces a versatile electrochemical sensing system-on-chip (SoC) for advanced electrochemical analysis and temperature monitoring. The multimodal chip integrates cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) with high precision and low power consumption.
Area of Science:
- Electrical Engineering
- Materials Science
- Biomedical Engineering
Background:
- Multimodal electrochemical sensing systems are crucial for advanced analytical applications.
- Existing systems often face limitations in dynamic range, impedance resolution, and temperature sensing accuracy.
- Integration of multiple sensing modalities onto a single chip (SoC) offers miniaturization and enhanced functionality.
Purpose of the Study:
- To present a novel multimodal electrochemical sensing system-on-chip (SoC).
- To integrate cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and temperature sensing functionalities.
- To achieve high performance metrics including adaptive range, high impedance resolution, and precise temperature measurement.
Main Methods:
- Designed and implemented a multimodal electrochemical sensing SoC using a 0.18 μm CMOS process.
- Developed adaptive readout circuitry for CV with automatic range adjustment and resolution scaling.
- Incorporated an impedance boost mechanism for EIS to extend detectable load impedance.
- Utilized a resistor-based temperature sensor with a swing-boosted relaxation oscillator.
Main Results:
- Achieved a 145.5 dB adaptive readout current range for CV.
- Obtained an EIS impedance resolution of 9.2 mΩ/√Hz at 10 kHz with <1% THD.
- Extended maximum detectable load impedance to 22.95 kΩ using the impedance boost mechanism.
- Demonstrated a temperature sensor resolution of 31 mK across 0-85 °C.
- The SoC operates at a total power consumption of 1 mW.
Conclusions:
- The developed multimodal electrochemical sensing SoC offers a highly integrated and efficient solution for various sensing applications.
- The system demonstrates superior performance in CV, EIS, and temperature sensing compared to existing technologies.
- The low power consumption and high precision make it suitable for portable and advanced analytical devices.
