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Updated: Jul 26, 2025
Author Spotlight: Development and Evaluation of a Standardized Rat Model for Calvarial Suture-Bony Composite Defects
Published on: May 10, 2024
Cognitive Development in Single-Suture Craniosynostosis - A Systematic Review
K Olsson1,2, J Engman1,3, D Nowinski2
1Rehabilitation Medicine, Uppsala University Hospital, Uppsala, Sweden.
None:
There is conflicting evidence whether single-suture craniosynostosis (SSC), is linked to adversities of cognitive development. To assess the evidence for a link between SSC and cognition, a systematic literature search was conducted and eligible studies assessed for inclusion by two independent readers. Forty-eight studies met inclusion criteria. Small to medium but persistent effects on both general and some specific cognitive functions across age bands were found in higher quality studies for SSC overall. There was limited evidence for effects related to surgical correction. Methodologies varied substantially and there was a lack of longitudinal studies using broad assessment batteries.
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