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Thinned-skull Cortical Window Technique for In Vivo Optical Coherence Tomography Imaging

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Real-time closed-loop tissue-specific laser osteotomy using deep-learning-assisted optical coherence tomography.

Yakub A Bayhaqi¹, Arsham Hamidi¹, Alexander A Navarini²

¹Biomedical Laser and Optics Group (BLOG), Department of Biomedical Engineering, University of Basel, 4123 Allschwil, Switzerland.

Biomedical Optics Express

|June 21, 2023

Summary

This summary is machine-generated.

This study introduces a novel real-time, noninvasive optical coherence tomography (OCT) method for laser osteotomy. This system uses deep learning to accurately detect bone and bone marrow during surgery, improving precision.

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Area of Science:

Biomedical Engineering
Medical Imaging
Surgical Technology

Background:

Laser osteotomy requires precise control to differentiate between bone and bone marrow.
Current methods lack real-time, noninvasive feedback for accurate tissue ablation.

Purpose of the Study:

To develop and validate a real-time, noninvasive feedback system for laser osteotomy using optical coherence tomography (OCT).
To assess the feasibility of using OCT with deep learning for intraoperative tissue identification during bone surgery.

Main Methods:

Implementation of optical coherence tomography (OCT) as an online feedback system for laser osteotomy.
Training a deep-learning model to identify bone and bone marrow during laser ablation.
Conducting hole ablation experiments to quantify perforation depth and volume loss.

Main Results:

The deep-learning model achieved a test accuracy of 96.28% in identifying tissue types.
Average maximum perforation depth was 0.216 mm, with an average volume loss of 0.077 mm³.
Demonstrated the feasibility of OCT for real-time feedback in laser osteotomy.

Conclusions:

Real-time OCT with deep learning offers a promising noninvasive solution for precise laser osteotomy.
The contactless nature and high accuracy of OCT support its integration as a feedback system in bone surgery.
This technology enhances surgical control and potentially reduces tissue damage during laser ablation procedures.